ncRNA name | mml-miR-126 |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Macaca mulatta |
Tissues/Cell_line | rhesus choroid-retinal endothelial cell line RF/6A |
Methods | qPCR, Western blot, scratch wound assay, transwell assay and tube formation assay, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | miR-126 overexpression inhibits the migration and sprouting of RF/6A cells induced by high glucose which might possibly be by blocking VEGFA and PIK3R2 in the VEGF/PI3K/AKT signaling pathway. |
PubMed ID | 28131600 |
Year | 2017 |
Title | MiR-126 overexpression inhibits high glucose-induced migration and tube formation of rhesus macaque choroid-retinal endothelial cells by obstructing VEGFA and PIK3R2. |
Drug-related ncRNA | NO |
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